Chicken Alfredo Lasagna

If comfort food had a crown, this Chicken Alfredo Lasagna would wear it. Imagine layers of tender lasagna noodles smothered in creamy, garlicky Alfredo sauce, interspersed with juicy rotisserie chicken, tender spinach, and cheesy ricotta and mozzarella layers that pull apart in gooey, irresistible strands. Every bite is rich, cozy, and decadent—a dish that feels like a hug straight from the oven.

This recipe is perfect for weeknight indulgence or a weekend dinner with friends or family. Trust me, once you make it, this lasagna is going to become a staple in your rotation. It’s a little bit fancy, a little bit cozy, and a whole lot of deliciousness.

Recipe Origin

Lasagna has been a beloved Italian classic for generations, and Alfredo sauce—rich, buttery, and cheesy—brings a luxurious twist to the traditional tomato-based version. Combining these elements with rotisserie chicken gives you a shortcut to depth of flavor without hours of cooking. This recipe blends the best of classic Italian comfort with modern convenience.

It’s like Italian fine dining at home, without needing a culinary degree—just a little patience and some love for the creamy, cheesy, layered goodness.

Kitchen Tools You’ll Need

• Large skillet for making the Alfredo sauce
• Medium saucepan or pot for boiling lasagna noodles
• 9×13-inch baking dish
• Mixing bowls
• Wooden spoon or spatula
• Grater for cheeses
• Measuring cups and spoons

Print

Why You’ll Love Chicken Alfredo Lasagna

Creamy and Comforting

Rich Alfredo sauce, tender noodles, and melty cheeses make every bite indulgent and satisfying.

Protein-Packed

Rotisserie chicken adds flavor and protein without extra cooking stress.

Colorful and Fresh

Spinach adds a fresh, earthy layer that balances the richness of the cheese and cream.

Make-Ahead Friendly

You can assemble it ahead of time, refrigerate, and bake when ready, making dinner stress-free.

Crowd-Pleasing

Cheesy, creamy, and hearty—this lasagna hits all the right notes for kids and adults alike.

Chef’s Pro Tips for Perfect Results

• Cook noodles al dente: They’ll finish cooking in the oven, and you’ll avoid mushy layers.
• Mix cheeses evenly: Stir together Parmesan and ricotta for a smooth, creamy layer.
• Don’t overcook the Alfredo: Cook gently over low heat to prevent the cream from breaking.
• Layer thoughtfully: Spread sauce evenly and avoid overstuffing any layer for perfect lasagna slices.

Ingredients in Chicken Alfredo Lasagna

Here’s what makes this lasagna irresistible:

Butter

Creates a rich base for the creamy Alfredo sauce.

Garlic

Finely minced for a fragrant, savory kick.

Yellow Onion

Adds subtle sweetness and depth to the sauce.

Fresh Baby Spinach

Bright, tender, and adds freshness that balances the creamy richness.

Heavy Cream

The heart of the Alfredo sauce—luxuriously creamy and velvety.

Whole Milk

Lightens the sauce slightly while keeping it rich and smooth.

Parmesan Cheese

Sharp, nutty, and perfectly melts into the sauce for flavor depth.

Ricotta Cheese

Soft, creamy, and perfect for layering between noodles and chicken.

Sea Salt and Black Pepper

Enhances and balances all the flavors in the dish.

Rotisserie Chicken

Cooked, shredded chicken adds protein and a flavorful shortcut.

Lasagna Noodles

The backbone of the dish, perfectly layered to hold all the goodness together.

Mozzarella Cheese

Melts beautifully to create gooey, golden, cheesy layers.

(Note: the full ingredients list, including measurements, is provided in the recipe card directly below.)

Instructions

Let’s make this creamy, cheesy masterpiece:

Preheat Your Oven

Set the oven to 375°F (190°C). Preheating ensures even baking and perfectly melted cheese.

Make the Alfredo Sauce

1. In a large skillet, melt butter over medium heat.
2. Add garlic and onion, sauté until fragrant and soft.
3. Stir in heavy cream and milk, bringing to a gentle simmer.
4. Mix in Parmesan cheese, salt, and pepper until smooth and creamy. Remove from heat.

Prepare the Noodle and Chicken Layers

1. Cook lasagna noodles according to package instructions until al dente. Drain and lay flat.
2. In a bowl, combine ricotta cheese and shredded rotisserie chicken. Mix gently to combine.

Assemble the Lasagna

1. Spread a thin layer of Alfredo sauce on the bottom of the baking dish.
2. Layer noodles over the sauce.
3. Spread a layer of the chicken-ricotta mixture over noodles.
4. Sprinkle baby spinach over the chicken mixture.
5. Drizzle with more Alfredo sauce and sprinkle shredded mozzarella on top.
6. Repeat layers until ingredients are used, finishing with a generous layer of mozzarella.

Bake to Perfection

1. Cover the lasagna with foil and bake for 25 minutes.
2. Remove foil and bake for an additional 10–15 minutes until the top is golden and bubbly.
3. Let it rest for 5–10 minutes before cutting to serve.

Serve and Enjoy

Cut into generous squares and serve warm. Pair with a fresh salad or garlic bread for the ultimate comfort meal.

Nutrition Facts

Servings: 8
Calories per serving: ~450
Prep Time: 15 minutes
Cook Time: 40 minutes
Total Time: 55 minutes

How to Serve Chicken Alfredo Lasagna

• With Garlic Bread: Perfect for sopping up extra sauce.
• With Fresh Salad: Arugula or Caesar salad provides a crisp, refreshing balance.
• Family Dinner: A crowd-pleaser that’s hearty and filling for everyone at the table.
• As Leftovers: Delicious cold or reheated for lunch the next day.

Make-Ahead and Storage Tips

• Assemble Ahead: Make the lasagna up to a day before and refrigerate. Bake when ready.
• Freeze for Later: Wrap tightly and freeze for up to 2 months. Bake from frozen, adding extra time.
• Reheat Leftovers: Microwave or bake in the oven until warmed through, keeping cheese melty.

Variations to Try

• Add Mushrooms: Sautéed mushrooms add an earthy depth to the filling.
• Spicy Twist: Sprinkle red pepper flakes into the sauce for a subtle kick.
• Vegetarian Version: Omit chicken and add roasted vegetables like zucchini or bell peppers.
• Cheese Blend: Mix mozzarella with provolone or fontina for a richer flavor.

Additional Tips

• Use Freshly Grated Cheese: It melts more smoothly and tastes richer than pre-shredded.
• Avoid Overcooking: Keep noodles al dente and bake just until bubbly for perfect texture.
• Layer Sauce Generously: Prevents dryness and ensures every bite is creamy.
• Let Rest Before Serving: Helps the layers set and makes cutting easier.

FAQ Section

Q1: Can I use pre-cooked or rotisserie chicken?
A1: Absolutely! It saves time and adds delicious flavor.

Q2: Can I make this ahead of time?
A2: Yes, assemble a day in advance and refrigerate. Bake when ready.

Q3: Can I freeze the lasagna?
A3: Yes, tightly wrap and freeze for up to 2 months. Bake from frozen.

Q4: Can I use gluten-free noodles?
A4: Yes, just adjust cook time according to the package instructions.

Q5: Can I use milk instead of cream?
A5: Whole milk works, but the sauce will be slightly less rich.

Q6: Can I add more spinach?
A6: Definitely! Just make sure to squeeze out excess water before layering.

Q7: Can I make it spicier?
A7: Add red pepper flakes or a pinch of cayenne to the Alfredo sauce.

Q8: Can I add extra cheese on top?
A8: Yes, a mix of mozzarella and Parmesan on top creates a golden, bubbly crust.

Q9: How do I prevent the lasagna from being watery?
A9: Make sure the chicken and spinach are not too wet, and use enough sauce between layers.

Q10: Can I use pre-shredded cheese?
A10: Yes, but freshly grated cheese melts better and tastes creamier.

Conclusion

Chicken Alfredo Lasagna is the ultimate comfort food—creamy, cheesy, and packed with flavor. It’s indulgent yet approachable, making it perfect for weeknights, family gatherings, or any time you want a hearty, satisfying meal. With its layers of tender noodles, flavorful chicken, fresh spinach, and creamy Alfredo sauce, this dish delivers on both taste and presentation.

Once you make this lasagna, it will quickly become one of your go-to recipes for any occasion. So grab your skillet, noodles, and cheeses—let’s get baking, because this creamy, cheesy masterpiece deserves a spot on your table tonight.

Learn how to make a creamy white chicken lasagna: